近藤恵祐

Keisuke Kondo

発表論文

9.

Sodium-lump-mediated mechanochemical deprotection of benzyl-derived groups

Kondo, K.; Shizukuishi, N.; Kubota, K.*; Ito, H.* Synthesis 2026, Just Accepted
DOI: 10.1055/a-2801-5094
8.

Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides

Kondo, K.; Lowe, M.; Davison, N.; Waddell, P. G.; Armstrong, R. J.*; Lu, E.*; Kubota, K.*; Ito, H.* Nature Synth. 2025, Accepted
DOI: 10.1038/s44160-025-00949-7

・北海道大学 PRESS RELEASE 「有機ナトリウム試薬の簡便かつ環境調和型な合成法の開発～豊富資源であるナトリウムを活用したサスティナブルな有機合成プロセスの実現へ～」
・Hokkaido University WPI-ICReDD PRESS RELEASE 「Towards sustainable organic synthesis – Mechanochemistry replaces lithium with sodium in organic reactions」
7.

Mechanochemical activation of metallic lithium for the generation and application of organolithium compounds in air

Kondo, K.; Kubota, K.*; Ito, H.* Nature Synth. 2025, 4, 744–753.
DOI: 10.1038/s44160-025-00753-3

・北海道大学 PRESS RELEASE 「有機リチウム試薬の簡便かつ環境に優しい合成法の開発～溶媒使用量を劇的に削減可能な新規有機合成プロセスの構築へ～」
・WPI-ICREDD PRESS RELEASE 「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・Highlighted in Mirage News「Mechanochemistry Simplifies Organolithium Creation」
・Highlighted in EurekAlert「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・Highlighted in ScienMag「Mechanochemistry Delivers: An Easy Approach to Synthesizing Organolithium Compounds」
・Highlighted in Bioengineer.org「Mechanochemistry Delivers: An Easy Approach to Synthesizing Organolithium Compounds」
・Highlighted in AlphaGalileo「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・Highlighted in Phys.org「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
6.

Solid-State Aromatic Nucleophilic Fluorination: A Rapid, Practical, and Environmentally Friendly Route to N-Heteroaryl Fluorides

Kubota, K.*; Makino, T.; Kondo, K.; Seo, T.; Jin, M.; Ito, H.* Green Chem. 2025, 27, 1771–1776.
DOI: 10.1039/D4GC06362G
5.

Highly Efficient and Air-tolerant Calcium-based Birch Reduction Using Mechanochemistry

Kubota, K.*; Fukuzawa, Y.; Kondo, K.; Gao, Y.; Ito, H.* Chem. Lett. 2024, 53, upae060.
DOI: 10.1093/chemle/upae060
4.

Mechanochemistry enabling highly efficient Birch reduction using sodium lumps and D-(+)-glucose

Kondo, K.; Kubota, K.*; Ito, H.* Chem. Sci. 2024, 15, 4452–4457.
DOI: 10.1039/D3SC06052G
3.

Solid-state mechanochemical cross-coupling of insoluble substrates into insoluble products by removable solubilizing silyl groups: Uniform synthesis of nonsubstituted linear oligothiophenes

Kubota, K.*; Kondo, K.; Seo, T.; Jin, M.; Ito, H.* RSC Adv. 2023, 13, 28652–28657.
DOI: 10.1039/D3RA05571J
2.

An Improved Catalytic System for Solid-state Iridium(I)-catalyzed C–H Borylation Using Mechanochemistry

Kondo, K.; Kubota, K.*; Ito, H.* Chem. Lett. 2023, 52, 333–336.
DOI: 10.1246/cl.230081
1.

Insight into the Reactivity Profile of Solid-State Aryl Bromides in Suzuki-Miyaura Cross-Coupling Reactions Using Ball Milling

Kubota, K.*; Kondo, K.; Seo, T.; Ito, H.* Synlett 2022, 33, 898–902.
DOI: 10.1055/a-1748-3797