Organoelement
Ito Research Lab
We aim to develop globally competitive
researchers as pioneers of the academic field,
achieving the top-class research method and data.
Hajime Ito's Laboratory
The major research interests of this laboratory are the development of new synthetic reactions, the exploration of new organic materials, and the discovery of unprecedented phenomena in chemistry. Our current research projects include (1) the copper-catalyzed reactions of diboron for selective organoboron synthesis; (2) iridium-catalyzed C-H borylation reactions; (3) the mechanochromic luminescence of organogold complexes; and (4) the development of new enantio-convergent reactions for the efficient synthesis of optically active compounds. The environment of this research group is designed to inspire all of the group members, and to cultivate and nurture their creativity by providing an interesting mixture of different elements of chemical research, with research topics ranging from organic synthesis to the development of nanomaterials. In this laboratory, our students and young researchers will learn many practical techniques that they will be able to apply in various fields of chemical research, including organic synthesis, coordination chemistry, the development of homogeneous catalysts, asymmetric synthesis, luminescent materials, and the development of organic materials based on nanoarchitectures using a bottom-up approach.

PUBLICATIONS
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Sodium-lump-mediated mechanochemical deprotection of benzyl-derived groups
Kondo, K.; Shizukuishi, N.; Kubota, K.*; Ito, H.* Synthesis 2026, Just Accepted
DOI :10.1055/a-2801-5094
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Using Mechanochemistry to Activate Poly(vinyl chloride) as a Mechanotunable Brønsted-Acid-Releasing Reagent for Organic Synthesis
Kubota, K.*; Hisazumi, R.; Jana, K.; Jiang, J.; Endo, T.; Maeda, S.; Ito, H.* J. Am. Chem. Soc. 2026, 148, 1953 - 1962.
DOI :10.1021/jacs.5c20376
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Mechanochemical synthesis of organosodium compounds through direct sodiation of organic halides
Kondo, K.; Lowe, M.; Davison, N.; Waddell, P. G.; Armstrong, R. J.*; Lu, E.*; Kubota, K.*; Ito, H.* Nature Synth. 2025, Accepted
DOI :10.1038/s44160-025-00949-7
・北海道大学 PRESS RELEASE 「有機ナトリウム試薬の簡便かつ環境調和型な合成法の開発~豊富資源であるナトリウムを活用したサスティナブルな有機合成プロセスの実現へ~」
・Hokkaido University WPI-ICReDD PRESS RELEASE 「Towards sustainable organic synthesis – Mechanochemistry replaces lithium with sodium in organic reactions」
・北海道大学 PRESS RELEASE 「有機ナトリウム試薬の簡便かつ環境調和型な合成法の開発~豊富資源であるナトリウムを活用したサスティナブルな有機合成プロセスの実現へ~」 ・Hokkaido University […]
Contactus
- Professor Dr. Hajime Ito
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E-mail: hajitoeng.hokudai.ac.jp