Organoelement
Ito Research Lab
We aim to develop globally competitive
researchers as pioneers of the academic field,
achieving the top-class research method and data.
Hajime Ito's Laboratory
The major research interests of this laboratory are the development of new synthetic reactions, the exploration of new organic materials, and the discovery of unprecedented phenomena in chemistry. Our current research projects include (1) the copper-catalyzed reactions of diboron for selective organoboron synthesis; (2) iridium-catalyzed C-H borylation reactions; (3) the mechanochromic luminescence of organogold complexes; and (4) the development of new enantio-convergent reactions for the efficient synthesis of optically active compounds. The environment of this research group is designed to inspire all of the group members, and to cultivate and nurture their creativity by providing an interesting mixture of different elements of chemical research, with research topics ranging from organic synthesis to the development of nanomaterials. In this laboratory, our students and young researchers will learn many practical techniques that they will be able to apply in various fields of chemical research, including organic synthesis, coordination chemistry, the development of homogeneous catalysts, asymmetric synthesis, luminescent materials, and the development of organic materials based on nanoarchitectures using a bottom-up approach.

PUBLICATIONS
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Mechanochemical activation of metallic lithium for the generation and application of organolithium compounds in air
Kondo, K.; Kubota, K.*; Ito, H.* Nature Synth. 2025, Just Accepted
DOI :10.1038/s44160-025-00753-3
・北海道大学 PRESS RELEASE 「有機リチウム試薬の簡便かつ環境に優しい合成法の開発~溶媒使用量を劇的に削減可能な新規有機合成プロセスの構築へ~」
・WPI-ICREDD PRESS RELEASE 「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・Highlighted in Mirage News「Mechanochemistry Simplifies Organolithium Creation」
・Highlighted in EurekAlert「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・Highlighted in ScienMag「Mechanochemistry Delivers: An Easy Approach to Synthesizing Organolithium Compounds」
・Highlighted in Bioengineer.org「Mechanochemistry Delivers: An Easy Approach to Synthesizing Organolithium Compounds」
・Highlighted in AlphaGalileo「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・Highlighted in Phys.org「Mechanochemistry strikes again – A facile means for generating organolithium molecules」
・北海道大学 PRESS RELEASE 「有機リチウム試薬の簡便かつ環境に優しい合成法の開発~溶媒使用量を劇的に削減可能な新規有機合成プロセスの構築へ~」 ・WPI-ICREDD PRESS RELEASE 「Mech […]
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Solvent-free Zinc-mediated Béchamp Reduction Using Mechanochemistry
Kubota, K.*; Nagao, A.; Ito, H.* RSC Mechanochem. 2025, Just Accepted
DOI :10.1039/D4MR00138A -
Solid-State Aromatic Nucleophilic Fluorination: A Rapid, Practical, and Environmentally Friendly Route to N-Heteroaryl Fluorides
Kubota, K.*; Makino, T.; Kondo, K.; Seo, T.; Jin, M.; Ito, H.* Green Chem. 2025, 27, 1771 - 1776.
DOI :10.1039/D4GC06362G
Contactus
- Professor Dr. Hajime Ito
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E-mail: hajitoeng.hokudai.ac.jp